Biomarkers in motor neuron disease: a state of the art review
NS Verber, SR Shepheard, M Sassani… - Frontiers in …, 2019 - frontiersin.org
Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The
average life expectancy is 2 years, but with a broad range of months to decades. Biomarker
research deepens disease understanding through exploration of pathophysiological
mechanisms which, in turn, highlights targets for novel therapies. It also allows differentiation
of the disease population into sub-groups, which serves two general purposes:(a) provides …
group of conditions, all of which are relentlessly progressive and ultimately fatal. The
average life expectancy is 2 years, but with a broad range of months to decades. Biomarker
research deepens disease understanding through exploration of pathophysiological
mechanisms which, in turn, highlights targets for novel therapies. It also allows differentiation
of the disease population into sub-groups, which serves two general purposes:(a) provides …
[引用][C] Biomarkers in motor neuron disease: a state of the art review. Front Neurol 10: 291
NS Verber, SR Shepheard, M Sassani, HE McDonough… - 2019
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