Evaporation heat transfer characteristics of carbon dioxide (CO₂) in a horizontal tube are experimentally investigated. The test tube has an inner diameter of 6.0 mm, a wall thickness of 1.0 mm, and a length of 1.4 m. Experiments are conducted at saturation temperatures of 5 and 10 °C, mass fluxes from 170 to 320 kg/m²s and heat fluxes from 10 to 20 kW/m². Partial dryout of CO₂ occurs at a lower quality as compared to the conventional refrigerants due to a higher bubble growth within the liquid film and a higher liquid droplet entrainment, resulting a rapid decrease of heat transfer coefficients. The effects of mass flux, heat flux, and evaporating temperature are explained by introducing unique properties of CO₂, flow patterns, and dryout phenomenon. In addition, the heat transfer coefficient of CO₂ is on average 47% higher than that of R134a at the same operating conditions. The Gungor and Winterton correlation shows poor prediction of the boiling heat transfer coefficient of CO₂ at low mass flux, while it yields good estimation at high mass flux.