Objective Patient-centered studies have shown that several patients on thyroid hormone
replacement therapy for hypothyroidism exhibit persistent symptoms, including “brain fog.”
Here, we aimed to determine which of these specific symptoms are associated with brain
fog, identify patient-reported factors that modify these symptoms, and identify patient
concerns related to brain fog not included in thyroid-specific questionnaires. Methods A
survey on brain fog symptoms adapted from thyroid-specific patient-reported outcome was …