Brain-derived microvesicles confer sickness behaviours by switching on the acute phase response in the liver
Background: Autoantibodies to myelin oligodendrocyte glycoprotein (MOG) have been
identified in some patients with inflammatory demyelinating diseases including paediatric
multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), clinical isolated
syndrome (CIS), neuromyelitis optica (NMO), monophasic or relapsing optic neuritis and
longitudinally extensive transverse myelitis (LETM). A subset of patients with recurrent optic
neuritis (rON) although they are considered within the rubric of AQP4-seronegative NMO …
identified in some patients with inflammatory demyelinating diseases including paediatric
multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), clinical isolated
syndrome (CIS), neuromyelitis optica (NMO), monophasic or relapsing optic neuritis and
longitudinally extensive transverse myelitis (LETM). A subset of patients with recurrent optic
neuritis (rON) although they are considered within the rubric of AQP4-seronegative NMO …
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