This paper deals with the change of business models (BMs) due to Information and Communication Technologies (ICTs). Recent advances in ICTs have caused BM change to be indispensable in all businesses. This is even more essential in the industries, where there is a significant diffusion of ICTs, such as the entertainment and gaming industry. In the context of our analysis, we apply a specific methodology of managing BM change to Regency Casinos, ie, the leader in the Greek gaming market. The case study shows that each step of this methodology fits to the business transformation plan of the company; hence, it arises that the applied methodology, supplemented by a series of factors favoring scenarios for BM development, can be applied to an unstable business environment, as the environment of our study.