… In addition, CXCL10 is produced by β-cells, and suppresses β-cell … , CXCL10/CXCR3 system
plays a decisive role in the pathogenesis of T1D. Here we review CXCL10/CXCR3 system, …

… we believe that the CXCL10/CXCR3 system plays a decisive role in the pathogenesis of type
1 diabetes. In this short review article, we take a closer look at the CXCL10/CXCR3 system, …

… That, or so it seemed, was to be the fate of the chemokine CXCL10 and its receptor CXCR3
as promising therapeutic targets in type 1 diabetes (T1D). Yet in this issue of Diabetes, Lasch …

… recent-onset type 1 diabetes and five control subjects without diabetes. Islet cell … CXCL10
and CXCR3 in human autoimmune type 1 diabetes, we investigated the expression of CXCL10 …

… Although we did not find an association of the CXCL9 and CXCL10 polymorphisms with
type 1 diabetes in the German population, we cannot discard their role in other populations or …

… CXCL10 and CXCR3 expression in pancreatic islets of a new-onset type 1 diabetes patient
… similar to a very recent report on fulminant diabetes and enterovirus infection [29]. A role for …

… To shed light on these phenotypic changes, we measured serum levels of the CXCR3
ligands CXCL9, CXCL10 and CXCL11, together with IL-4, IL-6, IL-10, IFN-γ, TGF-β and BAFF, …

… Next, we examined the mRNA expression levels of CXCL10, CXCR3 and two other ligands
of CXCR3 (CXCL9 and CXCL11) in the pancreas, pancreatic LN and spleen at the same …

… type 1 diabetes (T1D), expecially in autoimmunity and -cell destruction. In particular circulating
CXCL10 level (the ligand of CXCR3) … the CXCL10/CXCR3 axis in newly onset of diabetes …

… We examined serum CXCL10 levels in two fulminant type 1 diabetic patients (cases 1 and
2) using enzyme-linked immunosorbent assay, as previously described (26). Serum samples …