Calciphylaxis in a patient with rheumatoid arthritis without renal failure and hyperparathyroidism: the possible role of long-term steroid use and protein S deficiency
C Korkmaz, E Du¨ ndar, I Zubaroğlu - Clinical rheumatology, 2002 - Springer
C Korkmaz, E Du¨ ndar, I Zubaroğlu
Clinical rheumatology, 2002•SpringerCalciphylaxis is a rare and life-threatening condition of progressive cutaneous necrosis
secondary to small and medium-sized vessel calcification that is seen almost exclusively in
patients with end-stage renal disease and hyperparathyroidism. We report a case of
calciphylaxis that may very well be due to a long-term steroid use in a rheumatoid arthritis
patient who had neither end-stage renal disease nor hyperparathyroidism. We also discuss
the possible role of protein S deficiency as a contributing factor.
secondary to small and medium-sized vessel calcification that is seen almost exclusively in
patients with end-stage renal disease and hyperparathyroidism. We report a case of
calciphylaxis that may very well be due to a long-term steroid use in a rheumatoid arthritis
patient who had neither end-stage renal disease nor hyperparathyroidism. We also discuss
the possible role of protein S deficiency as a contributing factor.
Abstract
Calciphylaxis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to small and medium-sized vessel calcification that is seen almost exclusively in patients with end-stage renal disease and hyperparathyroidism. We report a case of calciphylaxis that may very well be due to a long-term steroid use in a rheumatoid arthritis patient who had neither end-stage renal disease nor hyperparathyroidism. We also discuss the possible role of protein S deficiency as a contributing factor.
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