Calcium supplementation modifies the relative amounts of bile acids in bile and affects key aspects of human colon physiology

JR Lupton, G Steinbach, WC Chang, BC O'Brien… - The Journal of …, 1996 - Elsevier
Use of calcium supplements has increased dramatically in recent years yet little is known
about the effect of calcium supplementation on colon physiology. We supplemented 22
individuals with a history of resected adenocarcinoma of the colon, but currently free of
cancer, with 2000 or 3000 mg calcium for 16 wk. The effects of supplementation on
duodenal bile acids and important fecal characteristics including total fecal output, wet and
dry weight, pH, bile acids (in solids and in fecal water), and concentrations and total …
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