Cardiac transplantation from non-viremic hepatitis C donors
SR Patel, S Madan, O Saeed, DB Sims, JJ Shin… - The Journal of Heart and …, 2018 - Elsevier
BACKGROUND Hepatitis C (HCV) donors are rarely used for cardiac transplantation due to
historically poor outcomes. In 2015, nucleic acid testing (NAT) for viral load was added to the
routine work-up of organ donors, allowing for the distinction between subjects who remain
viremic (HCV Ab+/NAT+) and those who have cleared HCV and are no longer viremic (HCV
Ab+/NAT–). The American Society of Transplantation recently recommended that HCV
Ab+/NAT–donors be considered non-infectious and safe for transplantation. We present our …
historically poor outcomes. In 2015, nucleic acid testing (NAT) for viral load was added to the
routine work-up of organ donors, allowing for the distinction between subjects who remain
viremic (HCV Ab+/NAT+) and those who have cleared HCV and are no longer viremic (HCV
Ab+/NAT–). The American Society of Transplantation recently recommended that HCV
Ab+/NAT–donors be considered non-infectious and safe for transplantation. We present our …
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