… Central administration of endoplasmic reticulum stress … In our study, ICV and intra-hypothalamic
administration of ER stress inducer TG inhibited leptin and insulin-induced anorexia. In …

… if central administration of DNJ regulates anorexigenic effects … Central administration of DNJ
inhibits AMPK via the regulation … Accordingly, we propose that central administration of DNJ …

… of anorexigenic POMC in the hypothalamus, and these effects were related to olanzapine-…
that central administration of an ER stress inhibitor, TUDCA, or specific administration of …

… By binding to their receptors, insulin and leptin directly stimulate anorexigenic POMC
neurons and inhibit orexigenic NPY/AgRP neurons in the ARC to suppress food intake and to …

… reuptake inhibitor used for depression, can attenuate ER stress-induced “leptin resistance,”
ie, insensitivity to the anti-obesity hormone leptin. Treatment with tunicamycin, an ER stress-…

… , central administration of chemical chaperones inhibited … Orexigenic neuropeptide AgRP
and NPY, which are derived … In contrast, central administration of anorexigenic neuropeptide α-…

… Fasting further stimulates the expression of AgRP-specific ERAD-related transcripts. Notably,
most of these fasting-induced changes in the UPR pathway are specific to AgRP neurons, …

… Hypothalamic endoplasmic reticulum (ER) stress is a key mechanism leading to obesity. …
lipotoxicity and hypothalamic ER stress, leading to sympathetic inhibition, reduced brown …

… Endoplasmic reticulum stress … Central administration of CBX attenuates ER stress induced
by tunicamycin. … Carbenoxolone also inhibited palmitate-induced reactive oxygen species …

… Central administration of this drug to HFD (but not STD) rats … that activation of the orexigenic
agouti-related protein (AgRP) … ER stress in the VMH decreases SNS activity to inhibit BAT …