Central hypersensitivity in chronic pain after whiplash injury
M Curatolo, S Petersen-Felix… - The Clinical journal …, 2001 - journals.lww.com
Objective The mechanisms underlying chronic pain after whiplash injury are usually unclear.
Injuries may cause sensitization of spinal cord neurons in animals (central hypersensitivity),
which results in increased responsiveness to peripheral stimuli. In humans, the
responsiveness of the central nervous system to peripheral stimulation may be explored by
applying sensory tests to healthy tissues. The hypotheses of this study were:(1) chronic
whiplash pain is associated with central hypersensitivity;(2) central hypersensitivity is …
Injuries may cause sensitization of spinal cord neurons in animals (central hypersensitivity),
which results in increased responsiveness to peripheral stimuli. In humans, the
responsiveness of the central nervous system to peripheral stimulation may be explored by
applying sensory tests to healthy tissues. The hypotheses of this study were:(1) chronic
whiplash pain is associated with central hypersensitivity;(2) central hypersensitivity is …
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