Cerebrovascular disease is associated with an increased disease severity in patients with coronavirus disease 2019 (COVID-19): a pooled analysis of published …
G Aggarwal, G Lippi… - International Journal of …, 2020 - journals.sagepub.com
International Journal of Stroke, 2020•journals.sagepub.com
Introduction There is an urgent need to identify patients at high risk during the ongoing
coronavirus disease (COVID-19) pandemic. Whether a history of stroke is associated with
increased severity of disease or mortality is unknown. Method We pooled studies from
published literature to assess the association of a history of stroke with outcomes in patients
with COVID-19. Results A pooled analysis of 4 studies showed a∼ 2.5-fold increase in odds
of severe COVID-19. While a trend was observed, there was no statistically significant …
coronavirus disease (COVID-19) pandemic. Whether a history of stroke is associated with
increased severity of disease or mortality is unknown. Method We pooled studies from
published literature to assess the association of a history of stroke with outcomes in patients
with COVID-19. Results A pooled analysis of 4 studies showed a∼ 2.5-fold increase in odds
of severe COVID-19. While a trend was observed, there was no statistically significant …
Introduction
There is an urgent need to identify patients at high risk during the ongoing coronavirus disease (COVID-19) pandemic. Whether a history of stroke is associated with increased severity of disease or mortality is unknown.
Method
We pooled studies from published literature to assess the association of a history of stroke with outcomes in patients with COVID-19.
Results
A pooled analysis of 4 studies showed a ∼2.5-fold increase in odds of severe COVID-19. While a trend was observed, there was no statistically significant association of stroke with mortality in patients with COVID-19 infection.
Discussion
Our findings are limited by a small number of studies and sample size.
Conclusion
There is a ∼2.5-fold increase in odds of severe COVID-19 illness with a history of cerebrovascular disease.
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