▪ Abstract Dictyostelium is an accessible organism for studies of signaling via
chemoattractant receptors. Chemoattractant-mediated signaling events and components are
reviewed and presented as a series of connected modules, including excitation, inhibition, G
protein–independent responses, early gene expression, inositol lipids, PH domain-
containing proteins, cyclic AMP signaling, polarization acquisition, actin polymerization, and
cortical myosin. The network incorporates information from biochemical, genetic, and cell …