Chicory (Cichorium intybus L.) Root Extract Regulates the Oxidative Status and Antioxidant Gene Transcripts in CCl4-Induced Hepatotoxicity
YS El-Sayed, MA Lebda, M Hassinin, SA Neoman - PloS one, 2015 - journals.plos.org
The ability of Cichorium intybus root extract (chicory extract) to protect against carbon
tetrachloride (CCl4)-induced oxidative stress and hepatotoxicity was evaluated in male rats.
The rats were divided into four groups according to treatment: saline (control); chicory extract
(100 mg/kg body weight daily, given orally for 2 weeks); CCl4 (1 ml/kg body weight by
intraperitoneal injection for 2 consecutive days only); or chicory extract (100 mg/kg body
weight daily for 2 weeks)+ CCl4 injection on days 16 and 17. The levels of hepatic lipid …
tetrachloride (CCl4)-induced oxidative stress and hepatotoxicity was evaluated in male rats.
The rats were divided into four groups according to treatment: saline (control); chicory extract
(100 mg/kg body weight daily, given orally for 2 weeks); CCl4 (1 ml/kg body weight by
intraperitoneal injection for 2 consecutive days only); or chicory extract (100 mg/kg body
weight daily for 2 weeks)+ CCl4 injection on days 16 and 17. The levels of hepatic lipid …
Retraction: Chicory (Cichorium intybus L.) Root Extract Regulates the Oxidative Status and Antioxidant Gene Transcripts in CCl4-Induced Hepatotoxicity
After the publication of the article, we were notified of concerns about Figure 1. Specifically, it
was brought to our attention that Figure 1 appears to be composed of multiple gel fragments
spliced together in a single image. Furthermore, this figure was published previously in two
articles in The Egyptian Journal of Biochemistry and Molecular Biology [2][3], where the data
were reported to represent different experiments. One of these articles was subsequently
retracted due to these same concerns. The authors were not able to provide the original …
was brought to our attention that Figure 1 appears to be composed of multiple gel fragments
spliced together in a single image. Furthermore, this figure was published previously in two
articles in The Egyptian Journal of Biochemistry and Molecular Biology [2][3], where the data
were reported to represent different experiments. One of these articles was subsequently
retracted due to these same concerns. The authors were not able to provide the original …
以上显示的是最相近的搜索结果。 查看全部搜索结果