… chlorthalidone, as compared with hydrochlorothiazide, would reduce the risk of major
nonfatal cardiovascular disease … with hypertension who were receiving hydrochlorothiazide at …

… whether chlorthalidone (CTD) is superior to hydrochlorothiazide (HCTZ) in hypertension …
to evaluate the effects of CTD compared with HCTZ on cardiovascular event (CVE) rates. We …

… Relative to HCTZ, the number needed to treat … HCTZ in preventing cardiovascular events.
This cannot be attributed entirely to the lesser effect of HCTZ on office systolic blood pressure …

… Whenever differences between active interventions can be observed in trials of hypertensive
cardiovascular disease, these do not begin to emerge until 1 year after the beginning of the …

… of the class, but the guideline states that chlorthalidone is preferred on the basis of longer
half-life and proven trial reduction of cardiovascular disease. However, to our knowledge there …

… As typically prescribed, chlorthalidone in older adults was not associated with fewer adverse
cardiovascular events or deaths than hydrochlorothiazide. However, it was associated with …

… However, most thiazide prescriptions in the US are HCTZ rather than CTD, 4 potentially …
CTD with HCTZ for the treatment of hypertension to reduce major adverse CV events (MACEs) …

… trials to reduce cardiovascular events and … cardiovascular events.However, to our knowledge
there are no published randomized trials comparing chlorthalidone and hydrochlorothiazide…

… trials to reduce cardiovascular events and … cardiovascular events.However, to our knowledge
there are no published randomized trials comparing chlorthalidone and hydrochlorothiazide…

… it is unclear if there is prevalence in preventing cardiovascular events for either drug [ 15 ]. …
effects of chlorthalidone compared with hydrochlorothiazide on cardiovascular event (CVE) …