Choosing sheep (Ovis aries) as animal model for temporomandibular joint research: Morphological, histological and biomechanical characterization of the joint disc

DF Angelo, P Morouço, N Alves, T Viana, F Santos… - Morphologie, 2016 - Elsevier
Preclinical trials are essential to the development of scientific technologies. Remarkable
molecular and cellular research has been done using small animal models. However,
significant differences exist regarding the articular behavior between these models and
humans. Thus, large animal models may be more appropriate to perform trials involving the
temporomandibular joint (TMJ). The aim of this work was to make a morphological (anatomic
dissection and white light 3D scanning system), histological (TMJ in bloc was removed for …
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