Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer
C Bodelon, S Vinokurova, JN Sampson… - …, 2016 - academic.oup.com
Carcinogenesis, 2016•academic.oup.com
The relationship between chromosomal instability and integration of the human
papillomavirus (HPV) DNA into the host genome is not well understood. We found that
chromosomal instability increases with HPV integration and diagnosis. However,
chromosomal instability could occur without HPV integration.
papillomavirus (HPV) DNA into the host genome is not well understood. We found that
chromosomal instability increases with HPV integration and diagnosis. However,
chromosomal instability could occur without HPV integration.
Summary
The relationship between chromosomal instability and integration of the human papillomavirus (HPV) DNA into the host genome is not well understood. We found that chromosomal instability increases with HPV integration and diagnosis. However, chromosomal instability could occur without HPV integration.
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