… [5-7] Rather than providing another supplementary review of chronopharmacokinetics,
the aim of … clinical implications of chronopharmacokinetics for drug monitoring and prescribing. …

The importance of drug dosing time in pharmacokinetics, pharmacodynamics, and toxicity is
receiving increasing attention from the scientific community. In spite of mounting evidence …

Nearly all functions of the human body are organized across the 24 hours of the day. This is
also true for functions involved in the regulation of pharmacokinetics such as gastric …

… to circadian mechanisms of chronopharmacokinetics, and to … are translated into
chronopharmacokinetics and chronoeffects… In conclusion, mechanism-based …

… This paper is a brief overview of chronopharmacology, especially chronopharmacokinetics,
and its connection with the clinical interpretation of the meaning of the drug concentrations …

… Chronopharmacokinetics is derfined as the predictable rhythamical changes dependent on
… In this paper this is illustrated with the chronopharmacokinetics of cardiovascular drugs (â-…

The circadian rhythm is widely detected in plants, animals, fungi, and cyanobacterium. The
main function of the circadian rhythm is the optimization of metabolism and energy …

… Chronopharmacokinetics deals with the study of the temporal … In a chronopharmacokinetic
study many factors of variation … on methodological aspects of chronopharmacokinetics, we …

… Chronopharmacokinetic studies are performed at every step of the biotransformation ie, …
points for clinical pharmacist/pharmacy practitioners, concerning chronopharmacokinetics. …

… Oscillating Abcg2 in the intestine has been identified as a key determinant to
chronopharmacokinetics of sulfasalazine although the toxicological consequence was not tested …