[PDF][PDF] Clearance of influenza virus from the lung depends on langerin+CD11b-but not plasmacytoid dendritic cells

CH GeurtsvanKessel, MAM Willart… - Division of Labor …, 2009 - repub.eur.nl
Although dendritic cells (DCs) play an important role in mediating protection against
influenza virus, the precise role of lung DC subsets such as CD11b-and CD11b+
conventional DCs or plasmacytoid DCs in different lung compartments is currently unknown.
Early after intranasal infection, tracheal CD11b-CD11chi DCs migrated to the mediastinal
LN, acquiring costimulatory molecules in the process. This emigration from the lung was
followed by an accumulation of CD11b+CD11chi DCs into the trachea and lung interstitium …

Clearance of influenza virus from the lung depends on migratory langerin+CD11b but not plasmacytoid dendritic cells

CH GeurtsvanKessel, MAM Willart, LS van Rijt… - The Journal of …, 2008 - rupress.org
Although dendritic cells (DCs) play an important role in mediating protection against
influenza virus, the precise role of lung DC subsets, such as CD11b− and CD11b+
conventional DCs or plasmacytoid DCs (pDCs), in different lung compartments is currently
unknown. Early after intranasal infection, tracheal CD11b− CD11chi DCs migrated to the
mediastinal lymph nodes (MLNs), acquiring co-stimulatory molecules in the process. This
emigration from the lung was followed by an accumulation of CD11b+ CD11chi DCs in the …
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