Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study
P Okokhere, A Colubri, C Azubike… - The Lancet Infectious …, 2018 - thelancet.com
Background Lassa fever is a viral haemorrhagic disease endemic to west Africa. No large-
scale studies exist from Nigeria, where the Lassa virus (LASV) is most diverse. LASV
diversity, coupled with host genetic and environmental factors, might cause differences in
disease pathophysiology. Small-scale studies in Nigeria suggest that acute kidney injury is
an important clinical feature and might be a determinant of survival. We aimed to establish
the demographic, clinical, and laboratory factors associated with mortality in Nigerian …
scale studies exist from Nigeria, where the Lassa virus (LASV) is most diverse. LASV
diversity, coupled with host genetic and environmental factors, might cause differences in
disease pathophysiology. Small-scale studies in Nigeria suggest that acute kidney injury is
an important clinical feature and might be a determinant of survival. We aimed to establish
the demographic, clinical, and laboratory factors associated with mortality in Nigerian …
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