Clonidine as an adjuvant to local anesthetics for peripheral nerve and plexus blocks: a meta-analysis of randomized trials
DM Pöpping, N Elia, E Marret, M Wenk… - The Journal of the …, 2009 - pubs.asahq.org
The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains
unclear. The authors searched for randomized placebo-controlled trials testing the impact of
adding clonidine to local anesthetics for peripheral single-injection nerve or plexus blocks in
adults undergoing any surgery (except eye) without general anesthesia. Twenty trials (1,054
patients, 573 received clonidine) published 1992-2006 tested plexus (14 brachial, 1
cervical) and nerve blocks (2 sciatic/femoral, 1 midhumeral, 1 ilioinguinal/iliohypogastric, 1 …
unclear. The authors searched for randomized placebo-controlled trials testing the impact of
adding clonidine to local anesthetics for peripheral single-injection nerve or plexus blocks in
adults undergoing any surgery (except eye) without general anesthesia. Twenty trials (1,054
patients, 573 received clonidine) published 1992-2006 tested plexus (14 brachial, 1
cervical) and nerve blocks (2 sciatic/femoral, 1 midhumeral, 1 ilioinguinal/iliohypogastric, 1 …
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