Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events

A Squizzato, M Bellesini, A Takeda… - Cochrane Database …, 2017 - cochranelibrary.com
A Squizzato, M Bellesini, A Takeda, S Middeldorp, MP Donadini
Cochrane Database of Systematic Reviews, 2017cochranelibrary.com
Background Aspirin is the prophylactic antiplatelet drug of choice for people with
cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional
benefit for people at high risk and people with established cardiovascular disease. This is an
update to a previously published review from 2011. Objectives To review the benefit and
harm of adding clopidogrel to aspirin therapy for preventing cardiovascular events in people
who have coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease …
Background
Aspirin is the prophylactic antiplatelet drug of choice for people with cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional benefit for people at high risk and people with established cardiovascular disease. This is an update to a previously published review from 2011.
Objectives
To review the benefit and harm of adding clopidogrel to aspirin therapy for preventing cardiovascular events in people who have coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease, or were at high risk of atherothrombotic disease, but did not have a coronary stent.
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