Clozapine induced eosinophilia: An often neglected important adverse effect
PK Kadiyala, MA Ahmed, DA Pinto… - Indian Journal of …, 2015 - journals.lww.com
Eosinophilia, a nondose-dependent side-effect, is seen in around 1% of clozapine-treated
patients. It occurs during 1st year of treatment, mostly in the initial 4 weeks.[1, 3, 4] It is
considered as an allergic reaction with a transient course and spontaneous remission.
However, in some cases, it may predict subsequent neutropenia, myocarditis, eosinophilic
colitis, pancreatitis and toxic hepatitis.[3, 4] The manufacturer
patients. It occurs during 1st year of treatment, mostly in the initial 4 weeks.[1, 3, 4] It is
considered as an allergic reaction with a transient course and spontaneous remission.
However, in some cases, it may predict subsequent neutropenia, myocarditis, eosinophilic
colitis, pancreatitis and toxic hepatitis.[3, 4] The manufacturer
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