… , and with origins ofDNA replication. We also describe recent … protein kinases control the
progress of the initiation reaction.… the initiation of DNA replication in eukaryotic cells asa two-…

… systems in both yeasts and mammals are finally beginning to … deletion that disrupts replication
control. This hypothesis will … of both α- and β-globin. Therefore, the genes encoding these …

… For the chromosome replication cycle in eukaryotes, there are two important states that … for
initiation of DNA replication (pre-RC) and the other is the alignment of the chromosomes at the …

… The onset of genomic DNA synthesis requires precise interactions of specialized initiator …
where the replication machinery can be loaded. These sites, defined as replication origins, are …

… of replication timing in both yeasts and mammals and provide new promise for our understanding
of both the significance and mechanism of the replication … is developmental control. At …

… chromosomal replication does, including ORC (9). Amplification requires the 440-bp amplification
control … eLetters should provide substantive and scholarly commentary on the article. …

… The initiation of chromosome replication by its own initiation … the replication of the chromosome
by the episome replication … If both the chromosome and the F replication systems were …

… inter-initiation adder controls replication initiation, that division is controlled by an adder running
from replication-initation to division, … from the replication and division control. The model …

… to as replication origins throughout each chromosome. Research in the past two decades …
ODP are involved in coordinating chromosomal replication to other cellular processes such as …

… We concentrate on two sets of molecular interactions affecting nuclear organization of DNA
… foci are highly sensitive to CDK levels, suggesting that CDKs control replication initiation at a …