… Ca 2+ -ATPase), which regulates calcium transport in … of several erythrocyte diseases,
including sickle cell anaemia [39,49,… of calpain-1 may offer a therapeutic option against sickle cell …

… of red blood cells from patients with sickle cell disease and … Na+/K+ATPase ion pumps,
ensuring the activity of secondary … the cells and consequent activation of caspases and calpains…

… intensity-correlated Ca 2+ concentrations when comparing the … fueling the plasma membrane
Ca 2+ ATPase (PMCA) can … + -calmodulin complex (Ca-CaM) and activation of calpain, …

… therapy of sickle cell disease has been sickle red cell (SS RBC) volume, … Summarized data
comparing SS cRBC cation currents … Apyrase can, in addition to its ATPase activity, serve as a …

… We investigated the roles of Ca 2+ /PKC signaling pathway on RBC mechanical responses
… -induced improving effects on RBC deformability independent of calpain mechanism and …

… A comparison of the extgnt of erythrocyte shape modulation … on the physiological effects of
raising erythrocyte intracellular … of the ca“-Pase by calpain (calcium activated neutral protease, …

… and Ca 2+ in both SS cells and normal red blood cells (AA cells) … Indeed, erythrocyte
membrane Ca 2+ -ATPase is … normal donors or from sickle cell anemia patients homozygous for …

… deficient RBC with calcium resulted in conversion of procalpain to calpain and eventual
autoproteolytic inactivation of calpain itself, and extensive release of acid endopeptidase activity …

… , which has increased Ca2+-ATPase activity and can be further … of the Ca2'-ATPase with
calpain, the Ca2-ATPase is … aging of RBCs and such diseases as sickle cell anemia The goal of …

… sickle cell disease, this leads to an increased hemolysis, increased adhesion of RBCs to
endothelial cells, … Plasma membrane Ca2+-ATPase (PMCA) plays the same role and drives the …