[PDF][PDF] Comparative dissolution study of different brands of amoxicillin trihydrate capsules available in Bangladesh
NH Huda, YM Jhanker… - Stamford Journal of …, 2009 - researchgate.net
Stamford Journal of Pharmaceutical Sciences, 2009•researchgate.net
Commercially available twenty national and four multinational brands of Amoxicillin
Trihydrate capsules were studied in water for 60 minutes using USP reference dissolution
apparatus. All, except two national brands (Code: NB-8 and NB-15); complied with the
USPin vitro dissolution specification for drug release (not less than 80% of the labelled
amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases from
those two brands were 75% and 67% respectively within the specified time period.
Trihydrate capsules were studied in water for 60 minutes using USP reference dissolution
apparatus. All, except two national brands (Code: NB-8 and NB-15); complied with the
USPin vitro dissolution specification for drug release (not less than 80% of the labelled
amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases from
those two brands were 75% and 67% respectively within the specified time period.
Abstract
Commercially available twenty national and four multinational brands of Amoxicillin Trihydrate capsules were studied in water for 60 minutes using USP reference dissolution apparatus. All, except two national brands (Code: NB-8 and NB-15); complied with the USPin vitro dissolution specification for drug release (not less than 80% of the labelled amount of amoxicillin trihydrate should be dissolved in 60 minutes). Drug releases from those two brands were 75% and 67% respectively within the specified time period.
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