Comparative efficacy of 1% curcumin nanomicelle gel and 2% curcumin gel for treatment of recurrent aphthous stomatitis: a double-blind randomized clinical trial

M Bakhshi, A Mahboubi, MR Jaafari, F Ebrahimi… - Journal of Evidence …, 2022 - Elsevier
Objective Recurrent aphthous stomatitis (RAS) is a highly prevalent painful inflammatory
condition. Curcumin is currently used as a medicinal herb with optimal anti–inflammatory
properties for many inflammatory conditions. However, due to its low water solubility and
consequently low bioavailability, its nanoparticulate formulation has been considered for
use. This study aimed to compare the efficacy of topical application of 1% curcumin
nanomicelle gel and 2% curcumin gel for treatment of RAS. Methods This double-blind …
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