Comparing screening instruments to predict posttraumatic stress disorder

J Mouthaan, M Sijbrandij, JB Reitsma, BPR Gersons… - PLoS …, 2014 - journals.plos.org
PLoS One, 2014journals.plos.org
Background Following traumatic exposure, a proportion of trauma victims develops
posttraumatic stress disorder (PTSD). Early PTSD risk screening requires sensitive
instruments to identify everyone at risk for developing PTSD in need of diagnostic follow-up.
Aims This study compares the accuracy of the 4-item SPAN, 10-item Trauma Screening
Questionnaire (TSQ) and 22-item Impact of Event Scale-Revised (IES-R) in predicting
chronic PTSD at a minimum sensitivity of 80%. Method Injury patients admitted to a level-I …
Background
Following traumatic exposure, a proportion of trauma victims develops posttraumatic stress disorder (PTSD). Early PTSD risk screening requires sensitive instruments to identify everyone at risk for developing PTSD in need of diagnostic follow-up.
Aims
This study compares the accuracy of the 4-item SPAN, 10-item Trauma Screening Questionnaire (TSQ) and 22-item Impact of Event Scale-Revised (IES-R) in predicting chronic PTSD at a minimum sensitivity of 80%.
Method
Injury patients admitted to a level-I trauma centre (N = 311) completed the instruments at a median of 23 days and were clinically assessed for PTSD at 6 months. Areas under the curve and specificities at 80% sensitivity were compared between instruments.
Results
Areas under the curve in all instruments were adequate (SPAN: 0.83; TSQ: 0.82; IES-R: 0.83) with no significant differences. At 80% sensitivity, specificities were 64% for SPAN, 59% for TSQ and 72% for IES-R.
Conclusion
The SPAN, TSQ and IES-R show similar accuracy in early detection of individuals at risk for PTSD, despite differences in number of items. The modest specificities and low positive predictive values found for all instruments could lead to relatively many false positive cases, when applied in clinical practice.
PLOS
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