[HTML][HTML] Comparison of gene editing versus conventional breeding to introgress the POLLED allele into the US dairy cattle population

ML Mueller, JB Cole, TS Sonstegard… - Journal of Dairy …, 2019 - Elsevier
… , gene editing to produce high-genetic-merit polledintrogression of the POLLED allele into
both the US Holstein and Jersey cattle populations via conventional breeding or gene editing

Comparison of Gene Editing Versus Conventional Breeding to Introgress the POLLED Allele Into the Tropically Adapted Australian Beef Cattle Population

ML Mueller, JB Cole, NK Connors, DJ Johnston… - Frontiers in …, 2021 - frontiersin.org
… to use gene editing to produce high-genetic-merit polled cattle … this study simulated
introgression of the POLLED allele into a … population via conventional breeding or gene editing

[HTML][HTML] Simulation of introgression of the POLLED allele into the Jersey breed via conventional breeding vs. gene editing

ML Mueller, JB Cole, TS Sonstegard… - Translational Animal …, 2018 - ncbi.nlm.nih.gov
… ) genetic gain than conventional breeding. The greatest difference in NM$ within a mating
… This study demonstrates how gene editing to produce high-genetic merit-polled sires could …

Comparison of Gene Editing versus Conventional Breeding to Introgress the POLLED Allele into Dairy and Beef Populations

ML Mueller - 2019 - search.proquest.com
… for introgression of the POLLED allele. Therefore, the objectives of this research were to
model introgression of the POLLED allele via conventional breeding or gene editing into both …

[PDF][PDF] Simulation of introgression of the polled allele into the Holstein breed via conventional breeding versus gene editing

ML Mueller, JB Cole, TS Sonstegard… - … –Gene Editing, 2018 - ars.usda.gov
… Computer simulation was used to compare introgression of the polled allele into a dairy
cattle population via conventional breeding versus gene editing in three different polled mating

Breeding in an era of genome editing

EL Clark - Animal Breeding and Genetics, 2022 - Springer
… of the PC POLLED allele, and presented genome editing as a … species comparison and
transfer of the genetic mechanisms … naturally introgressing beneficial alleles from one breed into

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

W Tan, DF Carlson, CA Lancto… - Proceedings of the …, 2013 - National Acad Sciences
… We undertook the nonmeiotic introgression of the Celtic POLLED allele (… For comparison,
we designed CRISPR gRNAs that … suggest that gene editing can be incorporated into selection …

A deletion at the polled PC locus alone is not sufficient to cause a polled phenotype in cattle

SL Hennig, JR Owen, JC Lin, BR McNabb… - Scientific reports, 2022 - nature.com
… Although successful introgression of the P C allele was … in which gene editing reagents
are introduced into the zygote … as well as lower levels of mosaicism compared to IVT gRNAs. …

The impact of genome editing on the introduction of monogenic traits in livestock

JWM Bastiaansen, H Bovenhuis, MAM Groenen… - Genetics Selection …, 2018 - Springer
… An example is the polled allele that is desired to breed dairy … compared to introgression
from another (inferior) breed. This … Introduction of this allele into other cattle breeds by GE has …

Genome editing in livestock: Are we ready for a revolution in animal breeding industry?

J Ruan, J Xu, RY Chen-Tsai, K Li - Transgenic research, 2017 - Springer
… The ability to efficiently achieve interspecies allele introgression in … are introgressed by
genome editing, such genome edited … , the polled Holstein cattle produced by genome editing (…