Complement, inflammation and thrombosis

E Rawish, M Sauter, R Sauter… - British Journal of …, 2021 - Wiley Online Library
… both thrombosis and complementComplement-mediated thrombosis and its relevance
for disease. The interplay between complement activation and platelet-mediated thrombosis

Complement activation on platelets: implications for vascular inflammation and thrombosis

EI Peerschke, W Yin, B Ghebrehiwet - Molecular immunology, 2010 - Elsevier
… that enhanced platelet associated complement activation correlates with increased arterial
… a role for platelet mediated complement activation in vascular inflammation and thrombosis. …

Interactions between coagulation and complement—their role in inflammation

K Oikonomopoulou, D Ricklin, PA Ward… - Seminars in …, 2012 - Springer
… , with critical thrombotic and/or inflammatory complications. … between complement activation
and thrombosis may facilitate … thrombotic conditions that are characterized by complement-…

Platelets, complement, and contact activation: partners in inflammation and thrombosis

OA Hamad, J Bäck, PH Nilsson, B Nilsson… - Current Topics in Innate …, 2012 - Springer
thrombotic events is closely associated with complement and contact system activation, which
in turn leads to inflammation … platelets and the complement and contact activation systems …

[HTML][HTML] Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
… Conversely, platelets also provide a surface for complement activation in infectious diseases
and platelet-bound complement boosts the inflammatory functions of innate immune cells …

[HTML][HTML] Inflammation and thrombosis

CT Esmon - Journal of Thrombosis and haemostasis, 2003 - Elsevier
… coagulation mechanisms, inflammatory mediators appear … thrombosis, but they also dampen
inflammatory activity. Some insights into the evolution and linkages between inflammatory

Links between complement activation and thrombosis

W Ruf - 2019 - ashpublications.org
… primes monocytes for thrombosis and pathogenic aPL … of complement and coagulation
cascades not only plays crucial roles in thrombosis, but also regulates thrombo-inflammatory

Reprint of Crosstalk between inflammation and thrombosis

CT Esmon - Maturitas, 2008 - Elsevier
… minimize complement mediated … an inflammatory mediator, larger thrombi do form at the
sites of injury [78,79]. Thus, it appears quite likely that inflammation contributes to thrombosis in …

Potential influences of complement factor H in autoimmune inflammatory and thrombotic disorders

J Ferluga, L Kouser, V Murugaiah, RB Sim… - Molecular …, 2017 - Elsevier
Complement also appears to have … in complement effectors and regulators, including Factor
H, have been associated with familial and sporadic autoimmune inflammatorythrombotic

Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS

R Cofiell, A Kukreja, K Bedard, Y Yan… - Blood, The Journal …, 2015 - ashpublications.org
complement activation, systemic thrombotic microangiopathy (TMA), and vital organ damage.
We evaluated the effect of terminal complement … Eculizumab reduced terminal complement