… complement pathway, resulting in uncontrolled complement … of the alternative complement
pathway (complement inhibitor … ]), thrombomodulin, and complement factor H–related protein …

… not only prevented complement activation but also influenced inflammatory and thrombotic
… routes (eg, targeting complement, coagulation, or downstream inflammation) that lead to …

… complement and coagulation has fundamental clinical implications in the context of diseases
with an inflammatory pathogenesis, in which complement–… of the complement system with …

… a thrombin-dependent mechanism of complement activation by RBC-… inflammatory disorders
involving intravascular microvesicle release, for example, sickle cell disease or thrombotic …

… for prevention of thrombo-inflammation [133]. In a recent study, platelet deposition was
shown to be dependent on complement activation in a model of venous thrombosis [52]. This …

… Microparticles (MP) are small membrane-bound vesicles that circulate in the peripheral blood
and play active roles in thrombosis, inflammation and vascular reactivity. While MP can be …

… like the complement anaphylatoxin C5a [15]. Another potential impact of inflammation of the
… S in humans are associated with an increased risk of thrombosis [18]. It has been reported …

… Complement activation generates the C5b9 complex, which if deposited on cells causes
exposure of phosphatidylserine on the surface of cells, thus initiating activation of the …

… The inflammatory response and the activation of coagulation … on the critical role of thrombus
formation, which prevents the … in the development of thrombi in combination with activation of …

… The authors showed, in a tissue factor-dependent model of flow restriction-induced venous
thrombosis, that complement factors play a role in platelet activation and fibrin deposition 42 . …