… in thrombo‐inflammatory diseases … thrombosis, inflammation, and tissue damage. However,
recent studies have shown that these interactions also regulate the resolution of inflammation…

… to form thrombi in various tissues. It has become increasingly clear that the complement system,
part … Not only does complement influence prothrombotic disease, it is equally involved in …

… Finally, we document that VWF-mediated activation of the complement terminal pathway
alters endothelial antithrombogenic properties and initiates microvascular thrombosis. …

… by thrombosis … complement activation plays a role in APS pathogenesis, and the interaction
of C5a with its receptor C5aR leads to inflammation, placental insufficiency, and thrombosis (…

… play vital roles in morphogenesis, inflammation, thrombosis, wound healing, immune … been
found effective in taming immune and thrombotic injury in experimental animal models and in …

… by which mutations in FH result in systemic thrombotic angiopathies. Finally, the work in …
complement and its many modifiers in regulation of vessel integrity, hemostasis, and thrombosis …

… In vivo, neutrophil accumulation at the site of thrombus formation paralleled the time delay
… in acute coronary thrombi. Our data indicate that local complement effectors amplify the …

… the classical pathway of complement, and activation of complement contributes to … complement
and associated with increased tissue temperature, indicative for an ongoing inflammatory …

… therapies that are highly effective in protecting against thrombosis in aHUS, could be …
evidence for complement participating in the pathophysiology underlying the thrombotic diathesis …

… Dysregulated activation of the complement system can lead to various inflammatory … reactions
or prevent complement formation on inappropriate surfaces. The complement system can …