… of the anaphylatoxin receptor C3aR for platelet function and arterial thrombus formation marks an intersection point between innate immunity and thrombosis
RJ Sauter, M Sauter, ES Reis, FN Emschermann… - Circulation, 2018 - Am Heart Assoc
… complement cascade and platelet thrombus formation are initiated in close spatiotemporal
and functional proximity. The complement … of the central complement component C3 to C3b …
and functional proximity. The complement … of the central complement component C3 to C3b …
[HTML][HTML] Inflammation and severe cerebral venous thrombosis
S Hu, H Lee, H Zhao, Y Ding, J Duan - Frontiers in neurology, 2022 - frontiersin.org
… Upon activation, A1 astrocytes increase the expression of numerous genes of the classic
complement cascade and inflammatory factors that communicate with M1 microglia and …
complement cascade and inflammatory factors that communicate with M1 microglia and …
Complement component consumption in sepsis correlates better with hemostatic system parameters than with inflammatory biomarkers
D Lendak, D Mihajlovic, G Mitic, M Ubavic… - Thrombosis research, 2018 - Elsevier
… C4 complement components in prediction of sepsis outcome. The secondary aim was to
determine relationship between complement components and other inflammatory parameters, …
determine relationship between complement components and other inflammatory parameters, …
Complement and complement regulatory proteins as potential molecular targets for vascular diseases
J Acosta, X Qin, J Halperin - Current pharmaceutical design, 2004 - ingentaconnect.com
… , inflammation and thrombosis in the vascular wall. This paper reviews complement and
complement … and vascular diseases; it highlights complement and its regulators as potential …
complement … and vascular diseases; it highlights complement and its regulators as potential …
Mechanisms of thrombosis and cardiovascular complications in COVID-19
EM Page, RAS Ariens - Thrombosis Research, 2021 - Elsevier
… by the interactions between hyperactive coagulation and complement systems – induced
by hyper-inflammatory conditions, resulting in a pro-thrombotic state and diffuse tissue injury. …
by hyper-inflammatory conditions, resulting in a pro-thrombotic state and diffuse tissue injury. …
[HTML][HTML] Implication of platelets in immuno-thrombosis and thrombo-inflammation
Y Zaid, Y Merhi - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… and thrombosis, infection, and innate and adaptive immunity. This review focuses on the
involvement of platelets during immuno-thrombosis and thrombo-inflammation. … of complement …
involvement of platelets during immuno-thrombosis and thrombo-inflammation. … of complement …
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
K Sriram, PA Insel - Physiological reviews, 2021 - journals.physiology.org
… on inflammatory and other cells promotes complement activation … complement component
occurs and increases with tissue injury and inflammation by properdin and other inflammatory …
occurs and increases with tissue injury and inflammation by properdin and other inflammatory …
[HTML][HTML] Complement, thrombotic microangiopathy and disseminated intravascular coagulation
S Kurosawa, DJ Stearns-Kurosawa - Journal of intensive care, 2014 - Springer
… complement systems, it seems unlikely that one will be activated without the other. The
expectation is that complement will be activated in almost all thrombotic … microvascular thrombosis…
expectation is that complement will be activated in almost all thrombotic … microvascular thrombosis…
[HTML][HTML] Cell type-specific roles of NF-κB linking inflammation and thrombosis
M Mussbacher, M Salzmann, C Brostjan… - Frontiers in …, 2019 - frontiersin.org
… inflammatory immune response against invading pathogens. In this review we focus on the
cellular interactions that link inflammation with thrombotic … and a subsequent thrombus. They …
cellular interactions that link inflammation with thrombotic … and a subsequent thrombus. They …
The role of complement in autoimmune disease-associated thrombotic microangiopathy and the potential for therapeutics
… of a thrombotic event, with 68.5… thrombosis showing evidence of complement activation.
Although these findings and the benefits of complement inhibition support a role for complement …
Although these findings and the benefits of complement inhibition support a role for complement …