BACKGROUND: To compare venlafaxine and selective serotonin reuptake inhibitors
(SSRIs; fluoxetine, sertraline, paroxetine, fluvoxamine, and citalopram) in the treatment of
depression. METHODS AND MATERIALS: Meta-analysis of 34 randomized, double-blind
studies identified by a worldwide search of all research sponsored by Wyeth
Pharmaceuticals through January 2007. Patients were treated with venlafaxine (n= 4191;
mean dose 151 mg/day) or SSRIs (n= 3621); nine studies also included a placebo control …