Computational study of protein secondary structure elements: Ramachandran plots revisited

F Carrascoza, S Zaric, R Silaghi-Dumitrescu - Journal of Molecular …, 2014 - Elsevier
Potential energy surface (PES) were built for nineteen amino acids using density functional
theory (PW91 and DFT M062X/6-311**). Examining the energy as a function of the φ/ψ
dihedral angles in the allowed regions of the Ramachandran plot, amino acid groups that
share common patterns on their PES plots and global minima were identified. These
patterns show partial correlation with their structural and pharmacophoric features.
Differences between these computational results and the experimentally noted permitted …
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