Hypoxia represents the temporary or longer-term decrease or deprivation of oxygen in
organs, tissues, and cells after oxygen supply drops or its excessive consumption. Hypoxia
can be (para)-physiological—adaptive—or pathological. Thereby, the mechanisms of
hypoxia have many implications, such as in adaptive processes of normal cells, but to the
survival of neoplastic ones, too. Ischemia differs from hypoxia as it means a transient or
permanent interruption or reduction of the blood supply in a given region or tissue and …