During tumor progression, the size and location of the tumor are important factors closely
associated with the metastatic potential of the cancer as they largely govern tumor hypoxia
and angiogenesis. However, despite the achievements of previous studies, these critical
factors are poorly studied, mainly due to the lack of a flexible technique that can readily
control 3D tumor mimicking constructs and their spatial relations with vasculature. Here, a
novel tissue‐level platform consisting of a metastatic cancer unit (MCU) and a perfusable …