Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart
Existing evidence indicates that resveratrol, a red wine and grape-derived polyphenolic
antioxidant, can pharmacologically precondition the heart in a nitric oxide (NO)-dependent
manner. To further explore the role of NO in resveratrol-mediated cardioprotection, the
induction for the expression of the potential molecular targets of NO including VEGF and
KDR as well as iNOS and eNOS were examined by Western blot analysis and
immunohistochemistry. Two groups of rats were studied, one group of animals was fed …
antioxidant, can pharmacologically precondition the heart in a nitric oxide (NO)-dependent
manner. To further explore the role of NO in resveratrol-mediated cardioprotection, the
induction for the expression of the potential molecular targets of NO including VEGF and
KDR as well as iNOS and eNOS were examined by Western blot analysis and
immunohistochemistry. Two groups of rats were studied, one group of animals was fed …
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