Corneal Endothelial Cell Changes After Ahmed™ Valve and Molteno™ Glaucoma Implants
Ophthalmic Surgery, Lasers and Imaging Retina, 2011•journals.healio.com
BACKGROUND AND OBJECTIVE: Changes in corneal endothelial cell (CEC) indices 24
months after Ahmed valve (New World Medical, Inc., Rancho Cucamonga, CA) and single-
plate Molteno implants (Molteno Ophthalmic Limited, Dunedin, New Zealand) were
evaluated. PATIENTS AND METHODS: This cohort included Ahmed valve (29 eyes) or
single-plate Molteno (28 eyes) implants. Preoperative and postoperative central CEC
indices were compared. Main outcome measure was endothelial cell count. RESULTS …
months after Ahmed valve (New World Medical, Inc., Rancho Cucamonga, CA) and single-
plate Molteno implants (Molteno Ophthalmic Limited, Dunedin, New Zealand) were
evaluated. PATIENTS AND METHODS: This cohort included Ahmed valve (29 eyes) or
single-plate Molteno (28 eyes) implants. Preoperative and postoperative central CEC
indices were compared. Main outcome measure was endothelial cell count. RESULTS …
BACKGROUND AND OBJECTIVE
Changes in corneal endothelial cell (CEC) indices 24 months after Ahmed valve (New World Medical, Inc., Rancho Cucamonga, CA) and single-plate Molteno implants (Molteno Ophthalmic Limited, Dunedin, New Zealand) were evaluated.
PATIENTS AND METHODS
This cohort included Ahmed valve (29 eyes) or single-plate Molteno (28 eyes) implants. Preoperative and postoperative central CEC indices were compared. Main outcome measure was endothelial cell count.
RESULTS
Twenty-four months postoperatively, no difference in visual acuity improvement or decrease in antiglaucoma medications was observed between groups. The Molteno group showed better postoperative intraocular pressure control (P < .001). An 11.52% (Ahmed) and 12.37% (Molteno) reduction in CEC density (cells/mm2) and 3.78 (Ahmed) and 2.48 (Molteno) increase in CEC area (mm2) was observed, but no significant between-group difference in CEC density and area or corneal thickness.
CONCLUSION
Twenty-four months after Ahmed valve or Molteno implant, statistically significant quantitative (cell density) and minor qualitative (cell area) changes in central CEC were observed. Both groups appeared to have similar CEC damage.
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