[HTML][HTML] Correlating Chlamydia trachomatis infectious load with urogenital ecological success and disease pathogenesis
JP Gomes, MJ Borrego, B Atik, I Santo, J Azevedo… - Microbes and …, 2006 - Elsevier
The association of infectious burden of Chlamydia trachomatis with patient characteristics
and clinical disease may have implications for understanding disease pathogenesis. We
examined chlamydial load from 171 urine samples where load was based on copy number
of organisms per copy number of eukaryotic cells derived by real-time quantitative PCR.
High-(E, F, G) and low-prevalence (Ia, H, J, Ja) genotypes in the population had similar
loads, suggesting a similar propensity for replicating in vivo, despite their differential …
and clinical disease may have implications for understanding disease pathogenesis. We
examined chlamydial load from 171 urine samples where load was based on copy number
of organisms per copy number of eukaryotic cells derived by real-time quantitative PCR.
High-(E, F, G) and low-prevalence (Ia, H, J, Ja) genotypes in the population had similar
loads, suggesting a similar propensity for replicating in vivo, despite their differential …
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