[PDF][PDF] Correlation of HDL associated paraoxonase 1 with oxidative stress markers in hypertensive dyslipidemic patients
ABSTRACT Introduction: Paraoxonase 1 (PON 1) is an esterase, exclusively synthesised by
the liver and a high density lipoprotein-associated antioxidant enzyme. Aim: To determine
the PON 1 and oxidative stress markers and to find out the possible correlation between
them in hypertensive dyslipidemic patients. Materials and Methods: This study included 500
patients, out of which 250 were diagnosed with hypertension and the remaining 250 were
age matched individuals, which serve as controls. PON 1 activity was measured manually by …
the liver and a high density lipoprotein-associated antioxidant enzyme. Aim: To determine
the PON 1 and oxidative stress markers and to find out the possible correlation between
them in hypertensive dyslipidemic patients. Materials and Methods: This study included 500
patients, out of which 250 were diagnosed with hypertension and the remaining 250 were
age matched individuals, which serve as controls. PON 1 activity was measured manually by …
Abstract
Introduction: Paraoxonase 1 (PON 1) is an esterase, exclusively synthesised by the liver and a high density lipoprotein-associated antioxidant enzyme.
Aim: To determine the PON 1 and oxidative stress markers and to find out the possible correlation between them in hypertensive dyslipidemic patients.
Materials and Methods: This study included 500 patients, out of which 250 were diagnosed with hypertension and the remaining 250 were age matched individuals, which serve as controls. PON 1 activity was measured manually by using spectrophotometer, Malondialdehyde (MDA) by TBA method, Superoxide Dismutase (SOD) by Marklund and Marklund, lipid profile was measured by biochemistry auto-analyser.
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