Cost-effective plasmonic device for label-free streptavidin detection

BPC Júnior, JH De Oliveira, PHM Buzzetti… - Materials Letters, 2018 - Elsevier
BPC Júnior, JH De Oliveira, PHM Buzzetti, MGV Fressatti, JP Monteiro, LHC Amorin
Materials Letters, 2018Elsevier
NLS was used to prepare holed plasmonic substrates with high sensitivity to streptavidin
detection. SEM and AFM characterizations showed substrates with holes distribution of
240.1±27.8 nm and periodicity of 420.2±25.4 nm. These substrates showed a sensitivity of
382.40±11.60 nm/RIU in solutions with different refractive indexes. The sensor has
demonstrated high sensitivity in the biosensing of biotin-streptavidin. The immunoassay
showed a 1.8±0.3 nm LSPR peak redshift in the protein detection. This work forms a …
Abstract
NLS was used to prepare holed plasmonic substrates with high sensitivity to streptavidin detection. SEM and AFM characterizations showed substrates with holes distribution of 240.1 ± 27.8 nm and periodicity of 420.2 ± 25.4 nm. These substrates showed a sensitivity of 382.40 ± 11.60 nm/RIU in solutions with different refractive indexes. The sensor has demonstrated high sensitivity in the biosensing of biotin-streptavidin. The immunoassay showed a 1.8 ± 0.3 nm LSPR peak redshift in the protein detection. This work forms a foundation towards the cost-effective plasmonic biosensors.
Elsevier
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