Criteria for hyperinflammation developing in coronavirus disease‐19: analysis of two cohorts from different periods of the pandemic
Background Hyperinflammation (HI) developing in 2 nd week of COVID‐19 contributes to
the worse outcome. Because of relatively milder laboratory findings, available criteria for
classification of hemophagocytic lymphohistiocytosis or macrophage activation syndrome
could not be helpful. Methods Discovery cohort included symptomatic COVID‐19 patients
from Turkey, followed at hospital during the initial wave. Replication cohort consisted of
hospitalized patients from a later period; all required oxygen support and received …
the worse outcome. Because of relatively milder laboratory findings, available criteria for
classification of hemophagocytic lymphohistiocytosis or macrophage activation syndrome
could not be helpful. Methods Discovery cohort included symptomatic COVID‐19 patients
from Turkey, followed at hospital during the initial wave. Replication cohort consisted of
hospitalized patients from a later period; all required oxygen support and received …
[PDF][PDF] Criteria for hyperinflammation developing in coronavirus disease-19: analysis of two cohorts from different periods of the pandemic
MD Deniz, MD Fatih Kemik, MD Besim Fazil Agargun… - researchgate.net
Background Hyperinflammation (HI) developing in 2nd week of COVID-19 contributes to the
worse outcome. Because of relatively milder laboratory findings, available criteria for
classification of hemophagocytic lymphohistiocytosis or macrophage activation syndrome
could not be helpful. Methods Discovery cohort included symptomatic COVID-19 patients
from Turkey, followed at hospital during the initial wave. Replication cohort consisted of
hospitalized patients from a later period; all required oxygen support and received …
worse outcome. Because of relatively milder laboratory findings, available criteria for
classification of hemophagocytic lymphohistiocytosis or macrophage activation syndrome
could not be helpful. Methods Discovery cohort included symptomatic COVID-19 patients
from Turkey, followed at hospital during the initial wave. Replication cohort consisted of
hospitalized patients from a later period; all required oxygen support and received …
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