Cryptococcus neoformans survive and replicate in human microglia.
SC Lee, Y Kress, ML Zhao, DW Dickson… - … investigation; a journal …, 1995 - europepmc.org
SC Lee, Y Kress, ML Zhao, DW Dickson, A Casadevall
Laboratory investigation; a journal of technical methods and pathology, 1995•europepmc.orgBackground Cryptococcus neoformans (CN) is an opportunistic pathogen that can cause
fatal meningoencephalitis in patients with immune deficiency. Among the central nervous
system (CNS) cells that are infected by CN are perivascular microglia and macrophages.
Little is known about the interaction of CN and CNS phagocytes at the cellular level.
fatal meningoencephalitis in patients with immune deficiency. Among the central nervous
system (CNS) cells that are infected by CN are perivascular microglia and macrophages.
Little is known about the interaction of CN and CNS phagocytes at the cellular level.
Background
Cryptococcus neoformans (CN) is an opportunistic pathogen that can cause fatal meningoencephalitis in patients with immune deficiency. Among the central nervous system (CNS) cells that are infected by CN are perivascular microglia and macrophages. Little is known about the interaction of CN and CNS phagocytes at the cellular level.
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