Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile

N Wurtz, G Penant, P Jardot, N Duclos… - European Journal of …, 2021 - Springer
The emergence of COVID-19 disease due to SARS-CoV-2 at the end of 2019 was rapidly
associated with the isolation of the strain from co-culture onto VERO cells. These isolations
quickly made it possible to carry out the first tests for antiviral agents' susceptibility and drug
repurposing. However, it seems important to make an inventory of all the cells that can
support the growth of this virus and evaluate possible differences between isolates. In the
present work, we tested 4 strains of SARS-CoV-2 locally isolated on a panel of 34 cell lines …

[PDF][PDF] Culture of SARS-CoV-2 in a panel of laboratory cell lines

N Wurtz, G Penant, P Jardot… - Mediterranee …, 2020 - mediterranee-infection.com
… In this paper, we investigated the 58 susceptibility of a number of cells lines available in
our laboratory collection to 59 SARS-CoV-2. These cells were derived from a variety of
species and tissues routinely used 60 for the culture of micro-organisms. After inoculation
with … -4 80 dilution to observe possible differences in permissivity of cells with respect to
the virus. All 81 experiments involving …
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