DNA bioassay-on-chip using SERS detection for dengue diagnosis

HT Ngo, HN Wang, AM Fales, BP Nicholson… - Analyst, 2014 - pubs.rsc.org
Analyst, 2014pubs.rsc.org
A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a
bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after
a single reaction on the chip's surface without any washing step, making it simple-to-use and
reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the
dengue virus 4 were detected.
A novel DNA bioassay-on-chip using surface-enhanced Raman scattering (SERS) on a bimetallic nanowave chip is presented. In this bioassay, SERS signals were measured after a single reaction on the chip's surface without any washing step, making it simple-to-use and reducing the reagent cost. Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected.
The Royal Society of Chemistry
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