DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… a critical role for DNA methylation in developmental gene regulation. … DNA methylation in
mammalian cells. 5 In this review, we will discuss the fundamental aspects of DNA methylation

[HTML][HTML] DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… cells develop a stable and unique DNA methylation pattern that regulates tissue-… of
DNA methylation and demethylation in the nervous system. We will describe the DNA (de)methylation

DNA methylation and cancer

M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
… Moreover, unlike genetic alterations, DNA methylation is reversible what … DNA methylation
alterations in tumorigenesis encourages us to decode the human epigenome. Different DNA

[HTML][HTML] DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation

DNA methylation and gene expression

A Razin, H Cedar - Microbiological reviews, 1991 - Am Soc Microbiol
DNA was noted over 40 years ago, its role in the regulation of gene activity has become
apparent only recently (8, 12, 13, 62). The first indications that DNA methylation … by methylation

DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
methylation have identified numerous regions in which it is dynamically regulated. In this
Review, we discuss key concepts in the function of DNA methylation in … where DNA methylation

DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
… of DNA methylation, studies of which have provided insights into how DNA methylation
rise to the diverse array of defective DNA methylation patterns in human diseases. It should …

New concepts in DNA methylation

A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
DNA methylation in a greater depth. Second, we present a modified stochastic DNA methylation
… of both the de novo and the maintenance methylation process at CpG and non-CpG sites…

DNA methylation: past, present and future directions

KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
… complex with the DNA, resulting in a progressive loss of DNA methylation with each round …
extremely valuable in studying the role of DNA methylation in gene expression. Treatment of a …

Function and information content of DNA methylation

D Schübeler - Nature, 2015 - nature.com
… assign a function to the local presence of DNA methylation at particular genes has remained
… function of DNA methylation in mammals, and discusses the utility of DNA methylation as a …