Deficits in motor and cognitive functions in an adult mouse model of hypoxia-ischemia induced stroke

L Feng, CX Han, SY Cao, HM Zhang, GY Wu - Scientific Reports, 2020 - nature.com
Ischemic strokes cause devastating brain damage and functional deficits with few treatments
available. Previous studies have shown that the ischemia-hypoxia rapidly induces clinically
similar thrombosis and neuronal loss, but any resulting behavioral changes are largely
unknown. The goal of this study was to evaluate motor and cognitive deficits in adult HI mice.
Following a previously established procedure, HI mouse models were induced by first
ligating the right common carotid artery and followed by hypoxia. Histological data showed …

[引用][C] Deficits in motor and cognitive functions in an adult mouse model of hypoxia-ischemia induced stroke. Sci Rep 10 (1): 20646

L Feng, CX Han, SY Cao, HM Zhang, GY Wu - 2020
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