Design of an immobilized enzyme system for naringin hydrolysis at high-pressure

HAL Pedro, AJ Alfaia, J Marques, HJ Vila-Real… - Enzyme and Microbial …, 2007 - Elsevier
The effect of pressure was studied in an enzymatic reaction with an immobilized biocatalyst.
Naringinase immobilized by entrapment in calcium alginate beads was the biocatalyst used
to catalyze, at high-pressure, the hydrolysis of naringin to naringenin. These molecules have
great potential in the pharmaceutical industry due to their recognized anti-oxidant, anti-
inflammatory, anti-carcinogenic, anti-hypertensive and hypocholesterolemic effects. At high-
pressure, the influence of relevant parameters on naringinase catalytic activity such as …
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