Plants have developed two distinct mechanisms, ie, strategy I (reduction strategy) and II
(chelation strategy), to mobilize insoluble Fe (III) in the rhizosphere and transport it through
the plasma membrane. Arabidopsis thaliana and other dicots rely on strategy I. In this
strategy, the rhizosphere is first acidified by a PM-localized H+-ATPase, AHA2. Then,
FERRIC CHELATE REDUCTASE 2 (FRO2) reduces Fe (III) to soluble Fe (II). Finally, the
reduced Fe is taken up by a high-affinity transporter, IRON-REGULATED TRANSPORTER 1 …